HLA Class I ABC Mouse Monoclonal Antibody [Clone ID: W6/32]
$500.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | W6/32 |
|---|---|
| Application | ELISA, FC, ICC, IHC, IP |
| Recommended Dilution | Flow Cytometry: (1/300 starting dilution). ELISA, IP, WB, IHC-Frozen sections, ICC: do be determined by user. |
| Reactivity | Bovine, Feline, Human, Primate |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Membrane of human tonsil cells |
| Specificity | The antibody W6/32 recognizes virtually all nucleated human cells. It is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders. This antibody W6/32 is also suitable as a positive control for HLA tissue typing and crossmatching. |
| Buffer | PBS, pH~7.4 Label: Biotin State: Liquid purified Ig fraction Preservative: 15 mM Sodium Azide Label: Conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin. |
| Concentration | lot specific |
| Conjugation | Biotin |
| Storage | Store undiluted at 2-8°C.
DO NOT FREEZE! |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Background | HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta-2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. |
| Synonyms | MHC class I ABC, HLA Class 2 ABC |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.