Fcmr Rat shRNA Plasmid (Locus ID 548326)
SKU
TR702402
Fcmr - Rat, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
2 Weeks*
| Product Data | |
| Locus ID | 548326 |
|---|---|
| Synonyms | Faim3; Toso |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Format | Retroviral plasmids |
| Components | Fcmr - Rat, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 548326). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001014843, NM_001014843.1, NM_001014843.2, BC088197 |
| UniProt ID | Q5M871 |
| Summary | May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation (By similarity).[UniProtKB/Swiss-Prot Function] |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.