Sik2 Mouse shRNA Plasmid (Locus ID 235344)
SKU
TR511040
Sik2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
2 Weeks*
| Product Data | |
| Locus ID | 235344 |
|---|---|
| Synonyms | G630080D20Rik; Snf1lk2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Format | Retroviral plasmids |
| Components | Sik2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 235344). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_178710, NM_178710.1, NM_178710.2, NM_178710.3, BC152763 |
| UniProt ID | Q8CFH6 |
| Summary | Phosphorylates 'Ser-789' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and inhibiting activity of TORCs, the CREB-specific coactivators, like CRTC2/TORC2 and CRTC3/TORC3 in response to cAMP signaling (PubMed:29211348).[UniProtKB/Swiss-Prot Function] |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.