Ube2d2b Mouse shRNA Plasmid (Locus ID 73318)

SKU TR504824

Ube2d2b - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 73318
• Synonyms: 1700013N18Rik
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: Ube2d2b - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 73318). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: BC050749, NM_001276397, NM_028502, NR_003639, NM_001276397.1, NM_028502.2
• UniProt ID: Q6ZWY6
• Summary: Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection (By similarity). Plays a role in early maturation of the testis.[UniProtKB/Swiss-Prot Function]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient