ECSCR Human shRNA Plasmid Kit (Locus ID 641700)

SKU TR320828

ECSCR - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 641700
• Synonyms: ARIA; ECSM2
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: ECSCR - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 641700). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001077693, NM_001293739, NR_121659, NM_001077693.1, NM_001077693.2, NM_001077693.3, NM_001293739.1, BC146912, BC146913, NM_001077693.4, NM_001293739.2
• UniProt ID: Q19T08
• Summary: The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient