CAMKK2 Human shRNA Plasmid Kit (Locus ID 10645)

SKU TR320643

CAMKK2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 10645
• Synonyms: CAMKK; CAMKKB
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: CAMKK2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 10645). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001270485, NM_001270486, NM_006549, NM_153499, NM_153500, NM_172214, NM_172215, NM_172216, NM_172226, NM_172226.1, NM_172226.2, NM_153500.1, NM_172214.1, NM_172214.2, NM_153499.2, NM_172215.1, NM_172215.2, NM_172216.1, NM_006549.1, NM_006549.2, NM_006549.3, NM_001270486.1, NM_001270485.1, BC026060, BC026060.2, BC000318, NM_001270485.2, NM_172215.3, NM_172214.3
• UniProt ID: Q96RR4
• Summary: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient