Casein Kinase 1 alpha (CSNK1A1) Human shRNA Plasmid Kit (Locus ID 1452)

SKU TR320312

CSNK1A1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 1452
• Synonyms: CK1; CK1a; CKIa; HEL-S-77p; HLCDGP1; PRO2975
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: CSNK1A1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1452). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001025105, NM_001271741, NM_001271742, NM_001892, NM_001892.1, NM_001892.2, NM_001892.3, NM_001892.4, NM_001892.5, NM_001025105.1, NM_001025105.2, NM_001271742.1, NM_001271741.1, BC008717, BC008717.2, BC005905, BC007246, BC009186, BC020446, BC020745, BC021971, BC025371, BC040473, BC105984, NM_001271741.2, NM_001025105.3, NM_001271742.2, NM_001892.6
• UniProt ID: P48729
• Summary: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).[UniProtKB/Swiss-Prot Function]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient