Non Neuronal Enolase (ENO1) Human shRNA Plasmid Kit (Locus ID 2023)

SKU TR313211

ENO1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 2023
• Synonyms: ENO1L1; HEL-S-17; MPB1; NNE; PPH
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: ENO1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2023). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001201483, NM_001428, NM_001353346, NM_001428.1, NM_001428.2, NM_001428.3, NM_001201483.1, BC022545, BC022545.1, BC001810, BC004325, BC004458, BC009218, BC009912, BC011130, BC015641, BC021166, BC027725, BC050642, BC113034, NM_001428.5, NM_001201483.4
• UniProt ID: P06733
• Summary: This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient