HBA-T2 (HBB) Human shRNA Plasmid Kit (Locus ID 3043)

SKU
TR312512
HBB - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
2 Weeks*
Specifications
Product Data
Locus ID 3043
Synonyms beta-globin; CD113t-C; ECYT6
Vector pRS
E. coli Selection Ampicillin
Format Retroviral plasmids
Components HBB - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3043). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_000518, NM_000518.1, NM_000518.2, NM_000518.3, NM_000518.4, BC007075, BC007075.1, NM_000518.5
UniProt ID P68871
Summary The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.