HBS1L Human shRNA Plasmid Kit (Locus ID 10767)

SKU TR312506

HBS1L - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 10767
• Synonyms: EF-1a; eRF3c; ERFS; HBS1; HSPC276
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: HBS1L - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 10767). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001145158, NM_001145207, NM_006620, NM_006620.1, NM_006620.2, NM_006620.3, NM_001145158.1, NM_001145207.1, BC040849, BC040849.1, BC001465, NM_001363686, NM_001145158.2, NM_006620.4, NM_001145207.2
• UniProt ID: Q9Y450
• Summary: This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient