Galectin 3 (LGALS3) Human shRNA Plasmid Kit (Locus ID 3958)

SKU TR311753

LGALS3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 3958
• Synonyms: CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: LGALS3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3958). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001177388, NM_002306, NR_003225, NM_001357678, NM_002306.1, NM_002306.2, NM_002306.3, NM_001177388.1, BC053667, BC053667.1, BC001120, BC068068, BC128253, BC128403
• UniProt ID: P17931
• Summary: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient