Neuropilin 1 (NRP1) Human shRNA Plasmid Kit (Locus ID 8829)

SKU TR311093

NRP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 8829
• Synonyms: BDCA4; CD304; NP1; NRP; VEGF165R
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: NRP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 8829). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: BC007533, NM_001024628, NM_001024629, NM_001244972, NM_001244973, NM_003873, NR_045259, NM_001330068, NM_001024629.1, NM_001024629.2, NM_001024628.1, NM_001024628.2, NM_003873.1, NM_003873.2, NM_003873.3, NM_003873.4, NM_003873.5, NM_001244973.1, NM_001244972.1, BC007533.1, BC007737, BC007737.2, NM_003873.7
• UniProt ID: O14786
• Summary: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Nov 2020]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient