NIPP1 (PPP1R8) Human shRNA Plasmid Kit (Locus ID 5511)

SKU TR310230

PPP1R8 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 5511
• Synonyms: ARD-1; ARD1; NIPP-1; NIPP1; PRO2047
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: PPP1R8 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5511). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_002713, NM_014110, NM_138558, NM_138558.1, NM_138558.2, NM_002713.2, NM_002713.3, NM_014110.2, NM_014110.3, NM_014110.4, BC093017, BC093017.1, BC001597, BC003405, BC013360, NM_002713.4, NM_014110.5
• UniProt ID: Q12972
• Summary: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient