SET Human shRNA Plasmid Kit (Locus ID 6418)

SKU TR309516

SET - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 6418
• Synonyms: 2PP2A; I2PP2A; IGAAD; IPP2A2; MRD58; PHAPII; TAF-I; TAF-IBETA
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: SET - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 6418). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001122821, NM_001248000, NM_001248001, NM_003011, NM_003011.1, NM_003011.2, NM_003011.3, NM_001122821.1, NM_001248001.1, NM_001248000.1, BC032749, BC032749.1, BC014567, NM_001248000.2, NM_003011.4, NM_001248001.2, NM_001122821.2
• UniProt ID: Q01105
• Summary: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient