Ezrin (EZR) Human shRNA Plasmid Kit (Locus ID 7430)

SKU TR308420

EZR - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 7430
• Synonyms: CVIL; CVL; HEL-S-105; VIL2
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: EZR - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 7430). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001111077, NM_003379, NM_003379.1, NM_003379.2, NM_003379.3, NM_003379.4, NM_001111077.1, BC013903, BC013903.2, BC068458, NM_001111077.2, NM_003379.5
• UniProt ID: P15311
• Summary: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient