CARS Human shRNA Plasmid Kit (Locus ID 833)

SKU TR305647

CARS - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 833
• Synonyms: CARS; CYSRS; MCDDBH; MDBH; MGC:11246
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: CARS - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 833). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001014437, NM_001014438, NM_001194997, NM_001751, NM_139273, NR_036542, NM_001751.1, NM_001751.2, NM_001751.3, NM_001751.4, NM_001751.5, NM_001014437.1, NM_001014437.2, NM_139273.1, NM_139273.2, NM_139273.3, NM_001194997.1, NM_001014438.1, BC002880, BC002880.2, NM_139273.4, NM_001751.6, NM_001194997.2, NM_001014437.3
• UniProt ID: P49589
• Summary: This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient