Translation factor GUF1, mitochondrial (GUF1) Human shRNA Plasmid Kit (Locus ID 60558)

SKU TR304168

GUF1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 60558
• Synonyms: DEE40; EF-4; EF4; EIEE40
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: GUF1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 60558). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001345867, NM_001345868, NM_001345869, NM_021927, NM_021927.1, NM_021927.2, BC036768, BC036768.1, BC012338, NM_021927.3
• UniProt ID: Q8N442
• Summary: This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient