PPFIBP1 Human shRNA Plasmid Kit (Locus ID 8496)

SKU TR302350

PPFIBP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 8496
• Synonyms: hSGT2; hSgt2p; L2; SGT2
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: PPFIBP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 8496). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: BC001560, NM_001198915, NM_001198916, NM_003622, NM_177444, NM_177444.1, NM_177444.2, NM_003622.1, NM_003622.2, NM_003622.3, NM_001198915.1, NM_001198916.1, BC050281, BC022873, BC046159, BM272389, NM_003622.4
• UniProt ID: Q86W92
• Summary: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient