PRDM15 Human shRNA Plasmid Kit (Locus ID 63977)

SKU TR302293

PRDM15 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 63977
• Synonyms: C21orf83; PFM15; ZNF298
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: PRDM15 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 63977). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001040424, NM_001282934, NM_022115, NM_144771, NR_104257, NR_104258, NR_104260, NR_135464, NM_001040424.1, NM_001040424.2, NM_022115.1, NM_022115.2, NM_022115.3, NM_022115.4, NM_001282934.1, BC032305, BC067102, BM544857, BM755202
• UniProt ID: P57071
• Summary: Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Involved in early embryo development (By similarity). Plays also a role in induced pluripotent stem cells (iPSCs) reprogramming (PubMed:28740264).[UniProtKB/Swiss-Prot Function]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient