SIRT7 Human shRNA Plasmid Kit (Locus ID 51547)

SKU TR301690

SIRT7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 51547
• Synonyms: SIR2L7
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: SIRT7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 51547). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_016538, NM_016538.1, NM_016538.2, BC017305, BC017305.2, BC101791, BC101793
• UniProt ID: Q9NRC8
• Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient