Tnfrsf10b Mouse shRNA Plasmid (Locus ID 21933)

SKU TL516936

Tnfrsf10b - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 21933
• Synonyms: DR5; KILLER; Ly98; MK; TRAILR2; TRICK2A; TRICK2B; TRICKB
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: Tnfrsf10b - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 21933). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: BC065141, NM_020275, NM_020275.1, NM_020275.2, NM_020275.3, NM_020275.4
• UniProt ID: Q9QZM4
• Summary: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.[UniProtKB/Swiss-Prot Function]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient