PDE5A Human shRNA Plasmid Kit (Locus ID 8654)

SKU TL316826

PDE5A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 8654
• Synonyms: CGB-PDE; CN5A; PDE5
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: PDE5A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8654). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001083, NM_033430, NM_033431, NM_033437, NM_001083.1, NM_001083.2, NM_001083.3, NM_033437.1, NM_033437.2, NM_033437.3, NM_033430.1, NM_033430.2, BC126233, BM920622, BM978332, NM_033430.3, NM_001083.4
• UniProt ID: O76074
• Summary: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient