CEBP Alpha (CEBPA) Human shRNA Plasmid Kit (Locus ID 1050)

SKU TL316491

CEBPA - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 1050
• Synonyms: C/EBP-alpha; CEBP
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: CEBPA - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1050). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001285829, NM_001287424, NM_001287435, NM_004364, NM_004364.1, NM_004364.2, NM_004364.3, NM_004364.4, NM_001285829.1, NM_001287435.1, NM_001287424.1, BC027902, BC063874, BC160133, NM_004364.5, NM_001287424.2
• UniProt ID: P49715
• Summary: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient