Sodium Potassium ATPase (ATP1A1) Human shRNA Plasmid Kit (Locus ID 476)

SKU TL314602

ATP1A1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 476
• Synonyms: CMT2DD; HOMGSMR2
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: ATP1A1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 476). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_000701, NM_001001586, NM_001160233, NM_001160234, NM_000701.1, NM_000701.2, NM_000701.3, NM_000701.4, NM_000701.5, NM_000701.6, NM_000701.7, NM_001160233.1, NM_001160234.1, NM_001001586.1, BC003077, BC003077.2, BC001330, BC050359
• UniProt ID: P05023
• Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient