Cullin 3 (CUL3) Human shRNA Plasmid Kit (Locus ID 8452)

SKU TL313641

CUL3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 8452
• Synonyms: CUL-3; NEDAUS; PHA2E
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: CUL3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8452). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001257197, NM_001257198, NM_003590, NM_003590.1, NM_003590.2, NM_003590.3, NM_003590.4, NM_001257197.1, NM_001257198.1, BC039598, BC039598.1, BC031844, BC092409, NM_001257198.2, NM_003590.5
• UniProt ID: Q13618
• Summary: This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient