Oct4 (POU5F1) Human shRNA Plasmid Kit (Locus ID 5460)

SKU TL310267

POU5F1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 5460
• Synonyms: Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: POU5F1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 5460). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: BC020712, NM_001173531, NM_001285986, NM_001285987, NM_002701, NM_203289, NM_002701.1, NM_002701.2, NM_002701.3, NM_002701.4, NM_002701.5, NM_203289.1, NM_203289.2, NM_203289.3, NM_203289.4, NM_203289.5, NM_001173531.1, NM_001173531.2, NM_001285986.1, NM_001285987.1, BC117435, BC069246, BC117437, NM_002701.6
• UniProt ID: Q01860
• Summary: This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient