ICOS Ligand (ICOSLG) Human shRNA Plasmid Kit (Locus ID 23308)

SKU TL303997

ICOSLG - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 23308
• Synonyms: B7-H2; B7h; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: ICOSLG - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 23308). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001283050, NM_001283051, NM_001283052, NM_015259, NM_015259.2, NM_015259.3, NM_015259.4, NM_015259.5, NM_001283051.1, NM_001283052.1, NM_001283050.1, BC064637, BC064637.1, NM_001365759, NM_001283052.2, NM_001283050.2, NM_015259.6, NM_001283051.2
• UniProt ID: O75144
• Summary: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).[UniProtKB/Swiss-Prot Function]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient