PKM2 (PKM) Human shRNA Plasmid Kit (Locus ID 5315)

SKU TL302462

PKM2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 5315
• Synonyms: CTHBP; HEL-S-30; OIP3; p58; PK3; PKM2; TCB; THBP1
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: PKM2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 5315). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001206796, NM_001206797, NM_001206798, NM_001206799, NM_001316318, NM_002654, NM_182470, NM_182471, NM_002654.1, NM_002654.2, NM_002654.3, NM_002654.4, NM_002654.5, NM_182470.1, NM_182470.2, NM_182470.3, NM_182471.1, NM_182471.2, NM_182471.3, NM_001206797.1, NM_001206797.2, NM_001206798.1, NM_001206798.2, NM_001206799.1, NM_001206796.1, NM_001206796.2, BC000481, BC000481.2, BC007640, BC007952, BC012811, BC019265, BC023328, BC023592, BC035198, BC035487, BC094767, BC096823, NM_001206796.3, NM_182471.4, NM_001206799.2, NM_002654.6
• UniProt ID: P14618
• Summary: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient