EGFR Human shRNA Plasmid Kit (Locus ID 1956)

SKU TG320326

EGFR - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 1956
• Synonyms: ERBB; ERBB1; ERRP; HER1; mENA; NISBD2; PIG61
• Vector: pGFP-V-RS
• E. coli Selection: Kan
• Format: Retroviral plasmids
• Components: EGFR - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 1956). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
• RefSeq: NM_005228, NM_201282, NM_201283, NM_201284, NM_001346897, NM_001346898, NM_001346899, NM_001346900, NM_001346941, NM_201283.1, NM_201282.1, NM_201284.1, NM_005228.1, NM_005228.2, NM_005228.3, NM_005228.4, BC070081, BC094761, BC118665, BC128419, NM_201284.2, NM_201282.2, NM_201283.2
• UniProt ID: P00533
• Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient