Beclin 1 (BECN1) Human shRNA Plasmid Kit (Locus ID 8678)

SKU TG314484

BECN1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 8678
• Synonyms: ATG6; beclin1; VPS30
• Vector: pGFP-V-RS
• E. coli Selection: Kan
• Format: Retroviral plasmids
• Components: BECN1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 8678). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
• RefSeq: NM_001313998, NM_001313999, NM_001314000, NM_003766, NM_003766.1, NM_003766.2, NM_003766.3, NM_003766.4, BC010276, BC010276.1
• UniProt ID: Q14457
• Summary: This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient