PICK1 Human shRNA Plasmid Kit (Locus ID 9463)

SKU TG310436

PICK1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 9463
• Synonyms: PICK; PRKCABP
• Vector: pGFP-V-RS
• E. coli Selection: Kan
• Format: Retroviral plasmids
• Components: PICK1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 9463). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
• RefSeq: NM_001039583, NM_001039584, NM_012407, NM_001039584.1, NM_012407.1, NM_012407.2, NM_012407.3, NM_001039583.1, BC017561, BC017561.2, NM_012407.4
• UniProt ID: Q9NRD5
• Summary: The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient