BCL2 Human shRNA Plasmid Kit (Locus ID 596)

SKU TF316461

BCL2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided

Product Data

• Locus ID: 596
• Synonyms: Bcl-2; PPP1R50
• Vector: pRFP-C-RS
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Retroviral plasmids
• Components: BCL2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 596). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
• RefSeq: BC027258, NM_000633, NM_000657, NM_000633.1, NM_000633.2, NM_000657.1, NM_000657.2, BC027258.1, NM_000657.3, NM_000633.3
• UniProt ID: P10415
• Summary: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient