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XPD (ERCC2) (NM_000400) Human Recombinant Protein

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SKU
TP762657
Purified recombinant protein of Human excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2), transcript variant 1, full length, with N-GST and C-His tag, expressed in E.coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region full length of ERCC2
Tag N-GST and C-HIS
Predicted MW 114.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000391
Locus ID 2068
UniProt ID P18074
Cytogenetics 19q13.32
RefSeq Size 2355
RefSeq ORF 2280
Synonyms COFS2; EM9; TFIIH; TTD; TTD1; XPD
Summary The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Aug 2008
Protein Categories Growth Factors, Intracellular Proteins
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Nucleotide excision repair
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Other "XPD" proteins (4)
SKU Description Size Price
LC400141 Lyophilized ERCC2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC427299 Lyophilized ERCC2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400141 Transient overexpression lysate of excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY427299 Transient overexpression lysate of excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2), transcript variant 2 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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