RSPO3 (NM_032784) Human Recombinant Protein

SKU TP762635

Purified recombinant protein of Human R-spondin 3 homolog (Xenopus laevis) (RSPO3), full length, with N-GST and C-His tag, expressed in E.coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of RSPO3
• Tag: N-GST and C-HIS
• Predicted MW: 58.9 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_116173
• Locus ID: 84870
• UniProt ID: Q9BXY4
• Cytogenetics: 6q22.33
• RefSeq Size: 4583
• RefSeq ORF: 816
• Synonyms: CRISTIN1; PWTSR; THSD2
• Summary: This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]
• Protein Families: Druggable Genome, Secreted Protein