Cytochrome P450 26B (CYP26B1) (NM_019885) Human Recombinant Protein

SKU TP762329

Purified recombinant protein of Human cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1), Pro229-End, with N-terminal His tag, expressed in E.coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Pro229-End) of CYP26B1
• Tag: N-His
• Predicted MW: 31.8 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_063938
• Locus ID: 56603
• UniProt ID: Q9NR63
• Cytogenetics: 2p13.2
• RefSeq Size: 4567
• RefSeq ORF: 1536
• Synonyms: CYP26A2; P450RAI-2; P450RAI2; RHFCA
• Summary: This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
• Protein Families: Druggable Genome, P450
• Protein Pathways: Retinol metabolism