TOPBP1 (NM_007027) Human Recombinant Protein

SKU TP762303

Purified recombinant protein of Human topoisomerase (DNA) II binding protein 1 (TOPBP1), Lys892-Asp1146, with N-terminal His tag, expressed in E.coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Lys892-Asp1146) of TOPBP1
• Tag: N-His
• Predicted MW: 28.5 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_008958
• Locus ID: 11073
• UniProt ID: Q92547
• Cytogenetics: 3q22.1
• RefSeq Size: 5378
• RefSeq ORF: 4566
• Synonyms: Dpb11; TOP2BP1
• Summary: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]