DVL1 (NM_004421) Human Recombinant Protein

CAT#: TP762283

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Purified recombinant protein of Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), Met1-Tyr279, with N-terminal His tag, expressed in E.coli, 50ug



  View other "DVL1" proteins (4)

USD 249.00


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    • 50 ug


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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Met1-Tyr279) of DVL1
Tag N-His
Predicted MW 31.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, pH8.0, 8M Urea
Storage Store at -80°C after receiving vials.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_004412
Locus ID 1855
UniProt ID O14640
Cytogenetics 1p36.33
Refseq Size 2941
Refseq ORF 2010
Synonyms DRS2; DVL; DVL1L1; DVL1P1
Summary DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, ES Cell Differentiation/IPS
Protein Pathways Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway

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Other Versions

Frequently bought together (1)
DVL1 rabbit polyclonal antibody
    • 100 ul

USD 380.00

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