TGF beta Receptor III (TGFBR3) (NM_003243) Human Recombinant Protein

SKU TP762270

Purified recombinant protein of Human transforming growth factor, beta receptor III (TGFBR3), transcript variant 1, Gly531-Pro777, with N-terminal His tag, expressed in E.coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Gly531-Pro777) of TGFBR3
• Tag: N-His
• Predicted MW: 27.8 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_003234
• Locus ID: 7049
• UniProt ID: Q03167
• Cytogenetics: 1p22.1
• RefSeq Size: 4199
• RefSeq ORF: 2553
• Synonyms: betaglycan; BGCAN
• Summary: This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane