FIP200 (RB1CC1) (NM_014781) Human Recombinant Protein

SKU TP762107

Purified recombinant protein of Human RB1-inducible coiled-coil 1 (RB1CC1), transcript variant 1,Ala1241-End, with N-terminal His tag, expressed in E. coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Ala1241-End) of RB1CC1
• Tag: N-His
• Predicted MW: 40.7 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_055596
• Locus ID: 9821
• UniProt ID: Q8TDY2
• Cytogenetics: 8q11.23
• RefSeq Size: 6636
• RefSeq ORF: 4782
• Synonyms: ATG17; CC1; FIP200; PPP1R131
• Summary: The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
• Protein Families: Druggable Genome