ATG16L1 (NM_198890) Human Recombinant Protein

SKU TP761243

Purified recombinant protein of Human ATG16 autophagy related 16-like 1 (S. cerevisiae) (ATG16L1), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length ATG16L1
• Tag: N-His
• Predicted MW: 49.9 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_942593
• Locus ID: 55054
• UniProt ID: Q676U5
• Cytogenetics: 2q37.1
• RefSeq ORF: 1332
• Synonyms: APG16L; ATG16A; ATG16L; IBD10; WDR30
• Summary: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]