Nrf2 (NFE2L2) (NM_006164) Human Recombinant Protein
Purified recombinant protein of Human nuclear factor (erythroid-derived 2)-like 2 (NFE2L2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Specifications
Product Data | |
Description | Purified recombinant protein of Human nuclear factor (erythroid-derived 2)-like 2 (NFE2L2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence | A DNA sequence encoding human full-length NFE2L2 |
Tag | N-His |
Predicted MW | 67.6 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, 8M Urea, pH8.0. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_006155 |
Locus ID | 4780 |
Refseq Size | 2859 |
Cytogenetics | 2q31.2 |
Refseq ORF | 1815 |
Synonyms | HEBP1; IMDDHH; NRF2 |
Summary | This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015] |
Protein Families | Transcription Factors |
Citations (1)
The use of this Proteins has been cited in the following citations: |
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The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
,Sanghvi, VR;Leibold, J;Mina, M;Mohan, P;Berishaj, M;Li, Z;Miele, MM;Lailler, N;Zhao, C;de Stanchina, E;Viale, A;Akkari, L;Lowe, SW;Ciriello, G;Hendrickson, RC;Wendel, HG;,
Cell 2019
,PubMed ID 31398338
[NFE2L2]
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