KIAA0020 (PUM3) (NM_014878) Human Recombinant Protein

SKU TP760512

Purified recombinant protein of Human KIAA0020 (KIAA0020), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length KIAA0020
• Tag: N-His
• Predicted MW: 73.4 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_055693
• Locus ID: 9933
• UniProt ID: Q15397
• Cytogenetics: 9p24.2
• RefSeq Size: 2232
• RefSeq ORF: 1944
• Synonyms: HA-8; HLA-HA8; KIAA0020; PEN; PUF-A; PUF6; XTP5
• Summary: Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress (PubMed:21266351). Binds to double-stranded RNA or DNA without sequence specificity (PubMed:25512524). Involved in development of the eye and of primordial germ cells (By similarity).[UniProtKB/Swiss-Prot Function]