H3FT (HIST3H3) (NM_003493) Human Recombinant Protein
$515.00
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| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
Protein Sequence
A DNA sequence encoding the region (Met1-Ala13polyhistidinetone H3
|
| Tag | Tag Free |
| Predicted MW | 15.5 kDa |
| Concentration | Resuspend the protein to the desired concentration in proper buffer. |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Lyophilized from a sterile solution containing 20 mM PB, pH 7.4 |
| Endotoxin | < 0.1 EU per 1 µg of the protein by the LAL |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NP_003484 |
| Locus ID | 8290 |
| UniProt ID | Q16695 |
| Cytogenetics | 1q42.13 |
| RefSeq Size | 481 |
| RefSeq ORF | 408 |
| Synonyms | H3.4; H3/g; H3FT; H3t; HIST3H3 |
| Summary | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015] |
| Protein Pathways | Systemic lupus erythematosus |
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