IFNW1 (22-195, His-Tag) Human Recombinant Protein

SKU TP728130L

Recombinant human IFN-omega protein

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  LGCDLPQNHG LLSRNTLVLL HQMRRISPFL CLKDRRDFRF PQEMVKGSQL QKAHVMSVLH EMLQQIFSLF HTERSSAAWN MTLLDQLHTG LHQQLQHLET CLLQVVGEGE SAGAISSPAL TLRRYFQGIR VYLKEKKYSD CAWEVVRMEI MKSLFLSTNM QERLRSKDRD LGSS
• Tag: His-Tag
• Predicted MW: 20.9kDa (180aa)
• Concentration: 1mg/ml (determined by Absorbance at 280nm)
• Purity: > 95% by SDS-PAGE
• Buffer: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
• Bioactivity: Measured in a cytotoxicity assay using TF-1 human erythroleukemic cells. The ED50 range ≤0.07 ng/ml.
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
• Recommended Dilution: SDS-PAGE, Bioactivity
• Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_002168.1
• UniProt ID: P05000
• Synonyms: interferon omega-1, interferon alpha-II-1, interferon omega 1, IFNW1, IFN-omega 1
• Summary: IFN-omega, also known as interferon-omega, is a member of a family of proteins with antiviral, growth inhibitory and immunomodulatory activity. Type I IFNs consist of IFN alpha, beta, tau, and omega and bind to the type I IFN receptor, whereas IFN-gamma is the only type II IFN and is specific for the type II IFN receptor. IFN-omega is produced primarily in leukocytes in response to viral infection, and it has biological activities. Also, it was reported that IFN-omega could inhibit the growth of human tumors in vivo. Recombinant human IFN-omega, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
• Protein Families: Bioactivity, SDS-PAGE