Tnfrsf9 Mouse Recombinant Protein

SKU TP727189

Recombinant Mouse 4-1BB/TNFRSF9/CD137 (C-Fc)

Product Data

• Species: Mouse
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Val24-Leu187
• Tag: C-Fc
• Buffer: Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
• Note: Recombinant Mouse 4-1BB ligand receptor is produced by our Mammalian expression system and the target gene encoding Val24-Leu187 is expressed with a Fc tag at the C-terminus.
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: 12 months from date of despatch
• Shipping: Dry Ice

Reference Data

• Locus ID: 21942
• UniProt ID: P20334
• Synonyms: Secreted CD137 antigen ;Tumor necrosis factor receptor superfamily member 9 ;Tnfrsf9
• Summary: Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.