Rhesus Recombinant Protein

SKU TP727009

Recombinant Macaca nemestrina PCSK9(C-6His)

Product Data

• Species: Rhesus
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Gln31-Gln152&Ser153-Gln692
• Tag: C-His
• Buffer: Supplied as a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, 20% Glycerol, pH 7.4.
• Note: Recombinant Macaca nemestrina Proprotein Convertase Subtilisin/Kexin Type 9/PCSK9 is produced by our Mammalian expression system and the target gene encoding Gln31-Gln152&Ser153-Gln692 is expressed with a 6His tag at the C-terminus.
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: 12 months from date of despatch
• Shipping: Dry Ice

Reference Data

• Synonyms: Proprotein Convertase Subtilisin/Kexin Type 9; Proprotein Convertase 9; PC9; Subtilisin/Kexin-Like Protease PC9; PCSK9
• Summary: Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.