Calprotectin (S100A8) Human Recombinant Protein

SKU TP726902

Recombinant Human S100 Calcium Binding Protein A8/S100A8/Mrp8 (C-6His)

Product Data

• Species: Human
• Protein Source: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Glu93
• Tag: C-His
• Buffer: Supplied as a 0.2 um filtered solution of 20mMHEPES,150mMnacl,2.5mMEDTA,10% Glycerol,ph7.0.
• Note: Recombinant Human S100 Calcium Binding Protein A8 is produced by our E.coli expression system and the target gene encoding Met1-Glu93 is expressed with a 6His tag at the C-terminus.
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: 12 months from date of despatch
• Shipping: Dry Ice

Reference Data

• Locus ID: 6279
• UniProt ID: P05109
• Synonyms: Protein S100-A8;S100A8;Calgranulin-A;Cystic fibrosis antigen;Leukocyte L1 complex light chain;MRP-8
• Summary: Protein S100-A8 (also MRP8 and calgranulin A) is a calcium- and zinc-binding protein.It plays a prominent role in the regulation of inflammatory processes and immune response. S100A8 can induce neutrophil chemotaxis and adhesion. Its role as an oxidant scavenger has a protective role in preventing exaggerated tissue damage by scavenging oxidants. It can act as a potent amplifier of inflammation in autoimmunity as well as in cancer development and tumor spread.