IL2 Human Recombinant Protein

SKU TP726597

Recombinant Human Interleukin-2/IL-2(C145S)

Product Data

• Species: Human
• Protein Source: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Pro22-Thr153(Cys145Ser)
• Buffer: Lyophilized from a 0.2 um filtered solution of 10mM Acetata-Na, 5% Trehaiose, pH 4.5 .
• Note: Recombinant Human Interleukin-2(C145S) is produced by our E.coli expression system and the target gene encoding Pro22-Thr153(Cys145Ser) is expressed.
• Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Stability: 12 months from date of despatch
• Shipping: Ambient

Reference Data

• Locus ID: 3558
• UniProt ID: P60568
• Synonyms: Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin
• Summary: Recombinant Human Interleukin-2 is a highly purified protein with a molecular weight of approximately 15,300 Daltons. The chemical name is des-alanyl-1, serine-145 Human Interleukin-2. It is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the Human IL-2 gene, and the resulting expression clone encodes a modified Human IL-2. This recombinant form differs from native Interleukin-2 in following ways: it is not glycosylated; the molecule has serine substituted for cysteine at amino acid position 145; the aggregation state of molecule is likely to be different from that of native IL-2.
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus