Human CB1 Protein, hFc Tag

SKU TP724121

Human CB1 Protein, hFc Tag

Product Data

• Expression Host: HEK293
• Tag: C-Human Fc
• Predicted MW: The protein has a predicted molecular mass of 44.2 kDa after removal of the signal peptide.The apparent molecular mass of CB1-hFc is approximately 70-100 kDa due to glycosylation.
• Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
• Reconstitution Method: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
• Storage: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
• Stability: 12 months from date of despatch
• Shipping: Ambient

Reference Data

• Synonyms: CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR
• Summary: This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.