Epo (NM_007942) Mouse Recombinant Protein

SKU TP723842

Purified recombinant protein of Mouse erythropoietin (Epo)

Product Data

• Species: Mouse
• Expression Host: CHO
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse EPO, the region of Ala27-Arg192, from gene Accession# NM_007942.2
• Tag: Tag Free
• Predicted MW: 18.6 kDa
• Concentration: lot specific
• Purity: >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: The ED50 is 0.5 - 2.5 ng/ml, corresponding to a specific activity of 0.4 - 2 x 10^6 units/mg, determined by the dose dependent stimulation of TF-1 cells proliferation.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_031968
• Locus ID: 13856
• UniProt ID: P07321
• Cytogenetics: 5 76.5 cM
• RefSeq Size: 715
• RefSeq ORF: 576
• Summary: This gene encodes the glycoprotein hormone erythropoietin that regulates the production of red blood cells and biosynthesis of hemoglobin. The predominant expression of this gene shifts from the liver during fetal development to kidney in adults. A complete lack of the encoded protein causes embryonic lethal anemia in mice. The conditional inactivation of this gene in adult mice results in a chronic, normocytic and normochromic anemia. Transgenic mice expressing the human ortholog of this gene exhibit polycythemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]